MANF Polyclonal Antibody for Human(Homo sapiens) | EIAab.comMANF Polyclonal Antibody for Human(Homo sapiens)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > MANF(Gene name) > Human

MANF (Gene name),

Mesencephalic astrocyte-derived neurotrophic factor (Protein name ), MANF_HUMAN from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

MANF(ARMET;ARP);

Protein name:

Mesencephalic astrocyte-derived neurotrophic factor;

Alternative:

Protein ARMET;Arginine-rich protein;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

182

Sequence:

50:

100:

150:

182:

CKGCAEKSDY | IRKINELMPK | YAPKAASART | DL

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

SMR:

P55145

KEGG:

hsa:7873

MIM:

601916

Pfam:

PF10208

String:

P55145

UniGene:

Hs.436446

STRING:

9606.ENSP00000273628

Uniprot:

P55145

FOR

ELISA Kit for Human Mesencephalic astrocyte-derived neurotrophic factor

Cat.:

E9615r

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Human Mesencephalic astrocyte-derived neurotrophic factor

Cat.:

E9615h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Human Mesencephalic astrocyte-derived neurotrophic factor

Cat.:

E9615m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Human Mesencephalic astrocyte-derived neurotrophic factor

Cat.:

E9615b

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Human Mesencephalic astrocyte-derived neurotrophic factor

Cat.:

U9615b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Mesencephalic astrocyte-derived neurotrophic factor

Cat.:

U9615h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Mesencephalic astrocyte-derived neurotrophic factor

Cat.:

U9615m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human Mesencephalic astrocyte-derived neurotrophic factor

Cat.:

U9615r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Human Mesencephalic astrocyte-derived neurotrophic factor

Cat.:

P9615Rb-r

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human Mesencephalic astrocyte-derived neurotrophic factor

Cat.:

P9615Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human Mesencephalic astrocyte-derived neurotrophic factor

Cat.:

P9615Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human Mesencephalic astrocyte-derived neurotrophic factor

Monoclonal Antibody for Human Mesencephalic astrocyte-derived neurotrophic factor

Protein for Human Mesencephalic astrocyte-derived neurotrophic factor

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"A gene from human chromosomal band 3p21.1 encodes a highly conserved arginine-rich protein and is mutated in renal cell carcinomas."
Shridhar V. , Rivard S. , Shridhar R. , Mullins C. , Bostick L. , Sakr W. , Grignon D. , Miller O.J. , Smith D.I.
Oncogene12:1931-1939(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];DISCUSSION OF A PUTATIVE CANCER VARIANT
2.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2003-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Colon.
tissue: Eye.
4.

"The DNA sequence, annotation and analysis of human chromosome 3."
Muzny D.M. , Scherer S.E. , Kaul R. , Wang J. , Yu J. , Sudbrak R. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , more...
Nature440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."
Gevaert K. , Goethals M. , Martens L. , Van Damme J. , Staes A. , Thomas G.R. , Vandekerckhove J.
Nat. Biotechnol.21:566-569(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 25-39
tissue: Platelet.
6.

"MANF: a new mesencephalic, astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons."
Petrova P. , Raibekas A. , Pevsner J. , Vigo N. , Anafi M. , Moore M.K. , Peaire A.E. , Shridhar V. , Smith D.I. , Kelly J. , Durocher Y. , Commissiong J.W.
J. Mol. Neurosci.20:173-188(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 25-29;FUNCTION;SUBCELLULAR LOCATION;GLYCOSYLATION
7.

"Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry."
Brill L.M. , Salomon A.R. , Ficarro S.B. , Mukherji M. , Stettler-Gill M. , Peters E.C.
Anal. Chem.76:2763-2772(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Leukemic T-cell.
8.

"Armet, a UPR-upregulated protein, inhibits cell proliferation and ER stress-induced cell death."
Apostolou A. , Shen Y. , Liang Y. , Luo J. , Fang S.
Exp. Cell Res.314:2454-2467(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INDUCTION
9.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
10.

"The structure of the conserved neurotrophic factors MANF and CDNF explains why they are bifunctional."
Parkash V. , Lindholm P. , Peranen J. , Kalkkinen N. , Oksanen E. , Saarma M. , Leppanen V.-M. , Goldman A.
Protein Eng. Des. Sel.22:233-241(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.80 ANGSTROMS) OF 25-182;DOMAIN;DISULFIDE BONDS
11.

"Mutations in the arginine-rich protein gene, in lung, breast, and prostate cancers, and in squamous cell carcinoma of the head and neck."
Shridhar R. , Shridhar V. , Rivard S. , Siegfried J.M. , Pietraszkiewicz H. , Ensley J. , Pauley R. , Grignon D. , Sakr W. , Miller O.J. , Smith D.I.
Cancer Res.56:5576-5578(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISCUSSION OF A PUTATIVE CANCER VARIANT
12.

"Mutations in the arginine-rich protein gene (ARP) in pancreatic cancer."
Shridhar V. , Rivard S. , Wang X. , Shridhar R. , Paisley C. , Mullins C. , Beirnat L. , Dugan M. , Sarkar F. , Miller O.J. , Vaitkevicius V.K. , Smith D.I.
Oncogene14:2213-2216(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISCUSSION OF PUTATIVE CANCER VARIANTS

Product Feedback Wall

* Email:
*Comments: